Monday, August 13, 2018

Session I: Metabolic Reprograming in Homeostasis and Disease

Session Chairs: Nada Abumrad, PhD

7:30-8:15 AM Conference Check-In and Breakfast (Grand Ballroom Foyer Registration Desk)

8:30 AM Introduction and Presentation of the Kern Lectureship Award - Moshe Levi, MD, Georgetown University

9:00 AM Kern Lecture: “mTOR and Lysosomes in Growth Control” - David Sabatini MD, PhD, MIT Biology and Whitehead Institute

9:45 AM “Glucose and amino acid metabolism in cancer” - Jason Locasale, PhD, Pharmacology and Cancer Biology, Duke University

10:20 AM “Reprogramming Metabolism in NAFLD Using Novel Amino Acid Compositions” - Manu Chakravarthy, MD, PhD, Axcella Health, Inc.

10:35 AM Break

10:50 AM “AMPK restores metabolic homeostasis” - Daniel Garcia, PhD, Molecular and Cell Biology Laboratory, Salk Institute

11:25 AM “Acetyl-CoA Metabolism in Pancreatic Tumorigenesis” - Kathryn Wellen PhD, Cancer Biology, University of Pennsylvania

12:00 AM Lunch (Mountain View Patio)

1:20 PM Introduction to David L. Williams Lecture and Award - Mary Sorci-Thomas, PhD, Medical College of Wisconsin

1:25 PM David L. Williams Lecture: “Intersection of Insulin Action with Cholesterol and Bile Acid Metabolism” - Rebecca Anne Haeusler, PhD, Columbia University

2:00 PM “Mapping Human Metabolic Diversity and its Role in Disease Using Untargeted Metabolomics” - Mohit Jain MD, PhD, Medicine, University of California, San Diego

2:35 PM “Lipids Reprogram Metabolism Providing a Major Source for Histone Acetylation” - Matthew Hirschey PhD, Medicine, Endocrinology, Metabolism, and Nutrition, Duke University

3:10 PM Break

3:30 PM Introduction by co-chair Philipp Scherer, Ph.D. University of Texas-Southwestern. “Nutrient Regulation of Muscle Insulin Sensitivity” - Zoltan Pierre Arany, MD, PhD, Medicine, Perelman School of Medicine

4:05 PM “Trans-Endothelial Insulin Efflux in Skeletal Muscle Capillaries” - David Wasserman, PhD, Molecular Physiology and Biophysics, Vanderbilt University

4:40 PM “Fatty Acid Sensitive Regulation of the Insulin Receptor and AMPK Pathways” - Dmitri Samovski, PhD, Medicine, Nutritional Sciences, Washington University

5:15 PM Introduction by Josiane Broussard, PhD, Colorado State University. Young Investigator Presentation: “Monounsaturated Fatty Acid Synthesis Regulates Inflammation” - Autumn York, PhD, Immunobiology, Yale University

5:30 PM Introduction by Josianne Broussard, PhD, Colorado State University. Young Investigator Abstract Presentation: “A Lipid-Regulated miRNA Controls Intracellular Phosphatidylinositol Metabolism” - Syed Hamid, PhD, Smidt Heart Institute & Department of Biomedical Sciences, Cedars Sinai

5:45 PM Young Investigator Abstract Presentation: “Alveolar Macrophage Lipid Homeostasis and the Anti-Cancer Immune Response” - Alexandra Kuhlmann, Yale University

6:00 PM Poster Session (Grand Ballroom, Salons F-J)